Targeting the Blind Spot of Polycationic Nanocarrier-Based siRNA Delivery
نویسندگان
چکیده
منابع مشابه
Targeting the blind spot of polycationic nanocarrier-based siRNA delivery.
Polycationic nanocarriers attract increasing attention to the field of siRNA delivery. We investigated the self-assembly of siRNA vs pDNA with polycations, which are broadly used for nonviral gene and siRNA delivery. Although polyethyleneimine (PEI) was routinely adopted as siRNA carrier based on its efficacy in delivering pDNA, it has not been investigated yet why PEI efficiently delivers pDNA...
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ژورنال
عنوان ژورنال: ACS Nano
سال: 2012
ISSN: 1936-0851,1936-086X
DOI: 10.1021/nn301966r